Phospho egfr antibody
WebA-431 EGFR KO cells treated with EGF. Phospho-EGFR was detected at ~170 kDa using Invitrogen™ Phospho-EGFR (Tyr1068) Polyclonal Antibody (Cat. No. PA5-17848), phospho-SHC was detected at ~51 kDa using Invitrogen™ Phospho-SHC (Tyr239, Tyr240) Polyclonal Antibody (Cat. No. 44-830), phospho-MEK was detected at ~45 kDa using Web4% PFA plus methanol. Methanol only. This clone failed to immunoprecipitate EGFR Phospho (Tyr845) from whole cell extracts prepared from EGF-stimulated A-431 cells. This recombinant antibody clone is derived from clone A18028A. This clone is predicted to recognize the region corresponding to EGFR Phospho (Tyr845) in both rat (Tyr846) and …
Phospho egfr antibody
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WebEGFR (epidermal growth factor receptor), also known as HER-1, ErbB1, or ErbB, is a transmembrane receptor tyrosine kinase that binds a subset of the EGF family ligands including EGF, Amphiregulin, TGF-alpha, Betacellulin, Epiregulin, HB-EGF, and Epigen. WebAnti-EGFR (phospho Y992) antibody See all EGFR primary antibodies Description Rabbit polyclonal to EGFR (phospho Y992) Host species Rabbit Tested applications Suitable for: WB, IHC-P, ICC more details Species …
WebThis Anti-phospho-EGFR (Tyr845) Antibody is validated for use in IC, IF, IH, WB for the detection of phospho-EGFR (Tyr845). Anti-phospho-EGFR (Tyr845) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References WebThe antibody is preabsorbed to remove any reactivity toward either a non-phosphorylated EGFR peptide or a phosphorylated tyrosine peptide, irrespective of the sequence. Anti- Phospho-EGFR [pTyr1148] specifically recognizes epidermal growth factor receptor phosphorylated at tyrosine 1148 (approximately 170 kDa).
WebApr 12, 2024 · EGFR levels were slightly higher in resistant cells, but phospho-EGFR (pEGFR) levels were significantly lower in untreated resistant cells, which reduced further upon osimertinib treatment. ... Immunoblot analysis of extracts from PC9-osiR cells treated with DMSO or AU-16770 for 0 h, 8 h, 24 h, and 48 h with antibodies against EGFR signaling ... WebPhosphorylated EGFR and PI3K/Akt signaling kinases are expressed in circulating tumor cells of breast cancer patients Our findings demonstrate that circulating tumor cells express receptors and activated signaling kinases of the EGFR/HER2/PI3K/Akt pathway, which could be used as targets for their effective elimination.
WebAnti-EGFR Antibody 06-847 Sigma-Aldrich Anti-EGFR Antibody Download Zoom Anti-EGFR Antibody detects level of EGFR & has been published & validated for use in IP & WB. Anti-EGFR Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References Brochures Required Licenses
high red cell count symptomsWebJul 9, 2024 · Western blot analysis was carried out with multiple primary antibodies as follows: EPS8 (610144) and AKT (610860) were from BD Biosciences (San Jose, CA); vimentin (V6389) was from Millipore... high red countWebThe SH2 domain of PLCγ binds at phospho-Tyr992, resulting in activation of PLCγ-mediated downstream signaling. Phosphorylation of EGFR at Tyr1045 creates a major docking site for the adaptor protein c-Cbl, leading to receptor ubiquitination and degradation following EGFR activation. The GRB2 adaptor protein binds activated EGFR at phospho ... how many calories in a 44 oz pepsiWebPhospho-EGF Receptor (Tyr1173) (53A5) Rabbit mAb detects endogenous EGF receptors only when phosphorylated at Tyr1173. This antibody may cross-react with other activated … high red count bloodWebProduct name Anti-EGFR (phospho Y845) antibody [EPR2149Y] See all EGFR primary antibodies Description Rabbit monoclonal [EPR2149Y] to EGFR (phospho Y845) Host species Rabbit Tested applications Suitable for: Flow Cyt (Intra), Dot blot, WB, ICC/IF more details Unsuitable for: IHC-P Species reactivity Reacts with: Human Immunogen high red gloss potsWebJan 9, 2024 · The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt. Alias: Fold/Unfold high red bootsWebApr 11, 2024 · Figure 4 – Altered expression of target protein upon cell treatment demonstrates antibody specificity. (A) Western blot using Phospho-EGFR (Tyr 1068) antibody (Cat. No. PA5-17848) shows increased expression of phospho-EGFR with EGF treatment. Pre-treatment with EGFR antagonists (Gefitinib and Afatinib) resulted in … high red converse